Laboratory-scale production of (S)-reticuline, an important intermediate of benzylisoquinoline alkaloids, using a bacterial-based method
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چکیده
منابع مشابه
Chapter Iv: Production of (r, S)-reticuline and Downstream Benzylisoquinoline Alkaloids in Saccharomyces Cerevisiae
The benzylisoquinoline alkaloids (BIAs) are a diverse class of plant secondary metabolites that exhibit a broad range of pharmacological activities and are synthesized through biosynthetic pathways that exhibit complex enzyme activities and regulatory strategies. We have engineered yeast to produce the major branch point intermediate reticuline and downstream BIA metabolites from a commercially...
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Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids
Benzylisoquinoline alkaloids (BIAs) are among the most important plant secondary metabolites, in that they include a number of biologically active substances widely employed as pharmaceuticals. Isolation of BIAs from their natural sources is an expensive and time-consuming procedure as they accumulate in very low levels in plant. Moreover, total synthesis is challenging due to the presence of s...
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BACKGROUND Benzylisoquinoline is the structural backbone of many alkaloids with a wide variety of structures including papaverine, noscapine, codeine, morphine, apomorphine, berberine, protopine and tubocurarine. Many benzylisoquinoline alkaloids have been reported to show therapeutic properties and to act as novel medicines. Thus it is important to collect and compile benzylisoquinoline alkalo...
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abstract the present study was conducted to investigate the effect of using model essays on the development of writing proficiency of iranian pre-intermediate efl learners. to fulfill the purpose of the study, 55 pre- intermediate learners of parsa language institute were chosen by means of administering proficiency test. based on the results of the pretest, two matched groups, one as the expe...
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ژورنال
عنوان ژورنال: Bioscience, Biotechnology, and Biochemistry
سال: 2017
ISSN: 0916-8451,1347-6947
DOI: 10.1080/09168451.2016.1243985